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In people without excess liver fat, the same signal appears more through rising ketones and a warmer baseline than through a large liver-fat change

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It has been developed using Novo Nordisks proprietary protein-acylation technology, and is administered using an injection device

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The push for a standalone MDL follows research from Harvard and JAMA Ophthalmology indicating that GLP-1 drugs may increase the risk of NAION up to sevenfold