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GLP-1s are usually shots that a person injects into their skin once or a few times a week

Some people also notice temporary nausea or low energy early on, which typically improves with time and proper dose adjustments

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Common mistakes include injecting too quickly (causing tissue trauma), reusing needles (which dulls the tip and increases pain), and injecting cold medication (which intensifies discomfort)

The smaller the gauge number, the thinner the needle

In operational terms, fill-rate improvement strategies include (a) reducing patient cost-sharing (via coupons or savings cards), (b) expediting PA/appeals, (c) improving patient education on access programs, and (d) direct patient engagement (nurse follow-up)