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This conformational change is induced by 2GPI binding to a negatively charged anionic surface

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Clinical data supports this approach

Kocoshis SA, Merritt RJ, Hill S, Protheroe S, Carter BA, Horslen S, et al

While these findings are observational and require confirmation in prospective studies, they highlight the potential of GLP-1 therapies to influence long-term musculoskeletal and inflammatory outcomes in patients with diabetes. For more information: Betul Ibis, MD, can be reached at [email protected].