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August 2021: Ozempic Associated With Heightened Risk of Diabetic Retinopathy Study results focused on diabetic retinopathy (DR) in patients taking semaglutide found that a higher risk for DR complications were observed with semaglutide in patients with proliferative and non-proliferative DR at baseline. However, researchers do acknowledge that worsening DR can be from rapid drops in blood glucose levels from diabetic medications

Other studies have documented up-regulation of the Y1-R agonist, PYY 1-36 , in pancreatic islets after obesity surgery
