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muciniphila administration in HFD-fed mice could be replicated by administration of an N-terminal His-tagged purified PAS without signal sequence produced by and purified from E

When DNA is damaged, enzymes called PARPs use NAD+ to add ADP-ribose groups to proteins, which helps recruit other proteins involved in repairing the DNA damage

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As the placebo group continued to have an increasing (worsening) motor score over time, the exenatide-treated group demonstrated improvements, which remarkably remained after the treatment had been stopped for 3 months (weeks 48-60 on the graph below)

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