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GLP-1 medications (semaglutide and tirzepatide) are injected under the skin (subcutaneous), not into muscle Compounded GLP-1 medications come in multi-dose vials and require a syringe for accurate dosing Correct dosing is critical using a GLP-1 dose-to-units calculator helps prevent common mistakes The abdomen is the most commonly used injection site, but the thigh and upper arm are also safe options Rotate injection sites weekly to reduce irritation and improve medication absorption Always clean the injection site and remove air bubbles before injecting Never use medication that has been exposed to heat, sunlight, or freezing temperatures (especially important in Florida) Follow your healthcare providers instructions for dosing, storage, and injection technique GLP-1 medications are injectable treatments used for weight loss and metabolic support

obesity medicine physician, Massachusetts General Hospital, Boston, Mass

Tracking your doses across switches If you do choose to alternate, meticulous record-keeping becomes essential

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When satiety is enhanced, the individual tends to eat less