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C602 concluded with a follow-up analysis that used a randomized withdrawal design

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This is an important distinction that often causes confusion

This is not coincidental
(60) reviewed patients with DM who received GLP-1R agonists (n=20,288) and SGLT-2 inhibitors (n=81,152)
Unlike oral semaglutide (Rybelsus), which requires an empty stomach and 30-minute fasting window, orforglipron can be taken with or without food at any time of day
