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Since the body does not metabolize it, the calories are not absorbed in the digestive system, meaning it does not raise blood sugar or insulin levels

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Research shows semaglutide and tirzepatide have distinct efficacy profiles, with tirzepatide demonstrating greater average weight loss in head-to-head trials, but individual response varies significantly

In fact, the pharmacokinetics (how the drug is absorbed and processed) are designed for slow, steady release from a once-weekly injection