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Our findings reveal that exendin-4 and liraglutide significantly reduce hepatic cholesterol accumulation and suppress SREBP-2 expression, a crucial regulator of cholesterol metabolism, via activation of the SIRT6-AMPK pathway in PA-treated HepG2 cells

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First, observational studies evaluating drug effects inherently carry risks of confounding by indication and unmeasured confounding

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For most Indian patients Metformin remains the safest, most affordable and most effective starting point