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The loss of estrogen can result in increased abdominal fat, and the loss of testosterone can limit energy

There are limited drugdrug interactions and no dosing adjustments in patients with upper gastrointestinal disease, renal impairment or hepatic impairment
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There is no clinically proven best time
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3.7 Peroxisome Proliferator-Activated Receptors (PPAR) The only medication in this class that is currently in use is pioglitazone
