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The same study investigated the effects of exenatide in human umbilical vein endothelial cells, and it significantly increased NO production, and endothelial

These include progressive redness spreading beyond the immediate injection site, increasing warmth, swelling, purulent drainage, fever, or pain that worsens rather than improves over 24-48 hours

[DOI] [PubMed] [Google Scholar] Kim D, MacConell L, Zhuang D, Kothare PA, Trautmann M, Fineman M, Taylor K

The authors acknowledged a substantial variation in weight change over time

For people with gastritis, certain foods, stress, or medications can make these symptoms worse

And interestingly, this becomes very clear for some people