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Description
Tirzepatide for weight loss is not a first step for everyone
Patients taking warfarin or other coumarin anticoagulants should have their INR monitored more frequently when starting or adjusting Ozempic, as changes in diet, weight, or gastrointestinal function may indirectly affect anticoagulation control

The presence of obesity-related complications such as obstructive sleep apnea, metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD), or cardiovascular disease may justify longer treatment duration given the health benefits of sustained weight loss
Oral Formulation: Importantly, different formulations of the same medication (e.g., Ozempic, Wegovy, and Rybelsus) are not interchangeable despite containing semaglutide

Weight loss of about 2kg was similar in the two groups

MeSH search terms used were GLP-1RA or DPP-4 inhibitor
