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"Medi-Cal Rx Contract Drugs List (CDL) Update: GLP-1 Agonist Coverage Changes Effective January 1, 2026." Wegovy, Zepbound, and Saxenda removed from CDL for weight loss

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Indeed, reports that sAC / mice display impairments in both pancreatic insulin secretion and intraperitoneal glucose tolerance (40, 43) support our findings implicating sAC in GLP-1(2836) and/or overall GLP-1 biology

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The following features would enhance the value of an obesity therapeutic, but would likely be assessed in follow-up trials or even post-approval: Additional efficacy in obesity-related co-morbidities

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