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If approved, Wegovy will become the first oral GLP-1 indicated for chronic weight management

Before matching, patients in the trial eligible and expanded populations initiating semaglutide or tirzepatide were younger, more likely to be white and were more frequently prescribed sulfonylureas compared to sitagliptin or dulaglutide users

Annual rates of severe hypoglycemia ranged from 1.4 to 1.6/100 person-years and were higher among older patients

Adverse effects: Orlistat-associated acute kidney injury and enteric hyperoxaluria Investigating the reflection of Orlistat, acute kidney injury, and enteric hyperoxaluria is vital due to the rare yet serious adverse effects linked to Orlistat

Lifestyle changes, such as eating a healthier diet and getting regular exercise, remain cornerstones of long-term weight management

While it appears that most TC patients have improved ejection fraction and normal mortality, the data suggests that a subset of TC has increased mortality compared to the normal population