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The maintenance dose should be the highest tolerated dose for the patient (e.g

This matters enormously because cardiovascular disease and kidney damage are the leading causes of morbidity and mortality in lupus

Prescription medications have extensive Phase 3 clinical trial data with thousands of participants
57:101865 [PMC free article: PMC9981899] [PubMed: 36874396] 348

Common side effects that Aetna may require documentation of include nausea, constipation, and gastrointestinal issues during dose escalation
Based on this criterion, one case was removed
