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The presence of benign thyroid nodules does not require dose modifications, delayed initiation, or special monitoring beyond what is already recommended for the nodules themselves

Cardiologists recommended combined therapy for patients with established cardiovascular disease or high cardiovascular risk who were already on treatment with one of the two drugs and had an HbA1c above target

Lancet Diabetes Endocrinol 13(6):482493 Stefanakis K, Kokkorakis M, Mantzoros CS (2024) The impact of weight loss on fat-free mass, muscle, bone and hematopoiesis health: implications for emerging pharmacotherapies aiming at fat reduction and lean mass preservation

In principle, this did not change the overall pattern, attesting to the robustness of findings based on this general strategy