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BMI 30 kg/m BMI 27 kg/m 3

For example, some people notice nausea only when their dose is increased

Some users report improved efficacy when they switch from evening to morning injections, or vice versa

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Naturally, this raises the question of whether dosing has been optimised at the ideal sweet spot where efficacy, safety and cost are all in balance, and there is the best chance of long-term persistence
