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To view or add a comment, sign in A recent retrospective cohort study published in The Lancet Obstetrics, Gynaecology and Womens Health explores how menopausal hormone therapy may influence tirzepatide response in postmenopausal women with overweight or obesity

POMC, pro-opiomelanocortin

[4] [5] This occurs because tirzepatide's appetite-suppressing effectsmediated through hypothalamic pathways and delayed gastric emptyingresolve as drug levels decline

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A strong first month can be motivating, but patients should understand that early weight loss is often a mix of fat loss and fluid shifts
