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Variations in FTO and MC4R genes also influence appetite regulation and satiety, which indirectly affects gastric dynamics

Estimated glucose disposal rate (eGDR) is a validated tool to estimate insulin sensitivity in type 1 diabetes using HbA1c, waist circumference, and presence of hypertension (39)

doi:10.1152/physrev.00034.2006
doi: 10.4093/dmj.2021.0356

The high cost of these drugs prevents them from being widely used, especially in areas with lower incomes
