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Latest ozempic lawsuit information over claims Ozempic and Mounjaro (GLP-1 receptor agonist drugs) cause stomach paralysis, known as gastroparesis

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Glucagon-like peptide-1 (GLP-1) is an incretin peptide hormone mainly secreted by enteroendocrine intestinal L-cells

The proposed mechanism: the leucine substitution increases hydrophobicity, potentially stabilizing the signal peptide and improving receptor trafficking to the cell surface meaning more receptor, more drug response