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Mechanism of Action 15.4.9

doi: 10.1016/S0140-6736(21)00213-0 68 FriasJPDeenadayalanSErichsenLKnopFKLingvayIMacuraSet al

LY3298176, a novel long-acting GIP/GLP-1 coagonist, shows enhanced activity on weight loss and energy utilization whilst maintaining its efficacy for glycaemic control

This situation feels different from other drug classes because it is: diabetes and obesity are massive markets, and beyond the FDA approved indicated populations, theres a swath of people interested in getting their hands on GLP-1 agonists off-label to help them lose a few extra pounds

The extract contains a precise ratio of active compounds that research suggests can help reduce snacking frequency and increase feelings of fullness when taken regularly

These medications are legal to be taken for treating obesity in adults with a BMI equal to or larger than 30 kg/m2 as well as in patients with a BMI of 25 kg/m2 and larger (overweight)