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Other GLP-1 or GIP receptor agonists these should not be used concurrently with tirzepatide

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Persistent gastrointestinal symptoms, hydration concerns, or other tolerability issues may lead a prescriber to delay escalation

The pyridoxine in your semaglutide compound adds a supplemental dose on top of dietary intake, which provides a comfortable margin, particularly useful during periods of reduced food intake when dietary B6 may decrease

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