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Serious side effects are rare but may include: Skin issues (rash, blisters, peeling) Vision problems (blurred vision, loss of vision, double vision, eye pain, redness) Seizures Feeling cold, chills, or a low body temperature Cognitive issues (difficulty concentrating, speech problems, confusion, memory problems) Coma (loss of consciousness) Coordination problems Heart-related symptoms (pounding or irregular heartbeat, chest pain, shortness of breath) Altered mental state (inability to respond to surroundings or mood changes) Tiredness Gastrointestinal problems (diarrhea, vomiting, loss of appetite) Kidney issues (intense back or side pain, abnormal urine) Frequent urination, pain while urinating Signs of infection (fever) Bleeding or bruising problems Osteoporosis In general, higher doses of topiramate are associated with an increased risk of adverse reactions

Food sensitivities and histamine-rich foods In susceptible individuals, histamine-rich foods (aged cheeses, wine, fermented foods) or allergies can cause flushing, palpitations, or a sense of internal revving. Keeping a simple symptom and food diary for 12 weeks can help you spot patterns between your meals, drinks, and palpitations, especially when you overlay thyroid medication timing and stress levels

Some reports have suggested a potential increase in suicidality risk associated with semaglutide, though the preponderance of current evidence does not indicate a heightened risk ( 13 , 14 )

Early plateaus sometimes reflect inadequate dose titration, while later ones reflect genuine receptor adaptation

Step 3: Get your medication shipped or prepared for pickup once approved

It has become quite clear that, for the majority of people who have excess weight gain, it is next to impossible to shift it over the medium to short term