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Back Dupr, J (26 Sept 1964) 'An intestinal hormone affecting glucose disposal in man', The Lancet , 672-73

All participants who received at least one dose of the study medication (semaglutide or metformin) were included in the safety analyses

The effects of semaglutide were consistent in those using renin-angiotensin system (RAS) blockers and SGLT2 inhibition compared with those not on these therapies

Dosing protocols varied across clinical trials, with a daily 5-g dose predominantly administered, typically combined with 3 d/week of resistance training

Tf ligand-receptor-mediated exenatide-Zn(2+) complex oral-delivery system for penetration enhancement of exenatide

Delayed gastric emptying Slower transit tempers glycemic spikes and prolongs satiety