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Distributed by: AstraZeneca Pharmaceuticals LP Wilmington, DE 19850 Revised: March 2015 Instructions for Use SymlinPen (SM-lnPn) 60 (pramlintide acetate) Pen-Injector Read the Medication Guide and these Instructions for Use before you start using SYMLIN and each time you get a refill

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Patients with pre-specified post-baseline eye procedures (pan-retinal photocoagulation for proliferative or severe nonproliferative diabetic retinopathy, local photocoagulation for new vessels, and vitrectomy for diabetic retinopathy) were also considered as 3-step progressors regardless of actual change in ETDRS score from baseline

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