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Its appetite-suppressing effects stem from multiple proposed physiological mechanisms that target both central and peripheral pathways involved in hunger regulation

More than half of the participants were female (54.7%)

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However, some patients may experience persistent symptoms requiring dose adjustment or discontinuation, and side effects may recur with each dose increase

Lancet 394(10193):121130 [DOI] [PubMed] [Google Scholar] 28.Pietzsch JB (2011) Long-term cost-effectiveness of CPAP therapy in patients with moderate to severe OSA

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