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Together, these findings necessitate further investigations to ascertain whether coordinated inhibition of NMDA receptors in GLP-1 receptor neurons modulates neuronal activity beyond canonical feeding regions, such as the mesolimbic dopaminergic reward pathway

10.1152/ajpheart.00347.2005 63 NrgaardC

If you have accidentally taken a double dose, contact NHS 111 or your GP immediately for advice

doi: 10.1093/ajhp/zxaa413

As more GLP-1 prescriptions are written to manage not just diabetes and cardiovascular disease but also obesity, a key question emerges: What is the role of patient engagement and chronic disease management when prescribing these drugs

In addition, long-term use of GLP-1RAs may also have potential safety risks, such as pancreatitis (Shetty et al., 2022) and thyroid diseases ( 6 Discussion T2DM is a chronic disease characterized by hyperglycemia, which eventually leads to microvascular damage and macrovascular events, as well as complications related to peripheral vascular diseases