biotech news today obesity drugs glp-1 The race may have a new contender. ๐ Regeneron reported Phase 3 data showing its drug candidate delivered up to 19.3% weight loss at 48 weeks, approaching the efficacy seen GLP-1s and the Unintended Consequences
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Injectable GLP-1 RAs like liraglutide, semaglutide, and dulaglutide have been shown to significantly lower HbA1c and body weight in patients with T2DM

[DOI] [PMC free article] [PubMed] [Google Scholar] 148
Effects on liver Despite the lack of expression of GIPR (41, 191) and GLP-1R (192, 193) in hepatocytes, both GIP and GLP-1 have indirect effects on hepatic lipid and glucose metabolism (194)
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