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The medication may trigger systemic inflammation, affecting the ocular surface and contributing to dry eye symptoms

SCFAs induce white adipose tissue (WAT) to develop beige fat through increased expression of thermogenic and mitochondrial regulators, which include uncoupling protein 1 (UCP1) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1) [137-139]

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Lillys orforglipron, if approved as expected this month, will not only end Novos brief run as the only oral GLP-1 game in town, but it also comes with what may well be a consumer-friendly competitive edge