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The drug slows the digestive system and produces more insulin through the pancreas

Estudios experimentales han determinado que estos frmacos disminuyen la expresin de la metaloproteinasas 2, que se encargan del remodelamiento de la matriz extracelular, reduce la infiltracin monocitaria en el endotelio vascular, la expresin de molculas de adhesin celular y promueve el cambio fenotpico de los macrfagos M1 (pro-inflamatorios) al M2 (anti-inflamatorios)

That creates a cycle where you feel sick, eat less, then feel even worse because your blood sugar drops too low

Michael Law, a pharmaceutical policy researcher and academic director of the Centre for Health Policy at the University of Calgary, said there appears to have been a lot of back-and-forth discussions between the regulator and drug manufacturers given the timelines [Source: theglobeandmail.com/business/economy/article-apotex-fda-approval-generic-ozempic-drug-health-canada-decisions/]

van Eijk, R
Some patients notice it more after eating or when their appetite patterns shift, but overall, it remains a manageable and short-term experience for most users
