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doi: 10.1016/j.neuropharm.2024.109952

To a large extent, these changes are also characteristic of metabolic syndrome, which affects approximately 25% of the worlds adult population and is associated with insulin resistance, hypertension, dyslipidemia and obesity, factors that increasingly lead to cognitive impairment and brain atrophy

Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of alzheimers disease via the GLP-1R/SIRT1/GLUT4 pathway