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In my clinical opinion, patients with obesity or metabolic disease should not delay treatment

The injections slow down the flow of bile through the gallbladder and delay emptying by suppressing the release of the hormone that controls it

For the full retatrutide approval timeline and what comes next, see our complete retatrutide guide

2.1 Liver Benefits: A Potential NAFLD/NASH Breakthrough 2.1.1 Retatrutide and Liver Fat Reduction Non-alcoholic fatty liver disease (NAFLD) is now one of the most common chronic liver conditions worldwide

Lastly, although it is not necessarily a surgical complication per se , some patients do fail to lose weight (113)

Theres also a similar class of medications called dual GLP-1 and GIP receptor agonists, and tirzepatide (the generic name for Mounjaro and Zepbound) is the only drug available in the U.S