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A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

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Horlocker TT, Vandermeuelen E, Kopp SL, et al

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The high prevalence of GLP-1 use among patients with advanced MASH and comorbidities such as diabetes and obesity also highlights the importance of considering GLP-1 as part of combination therapies in the development of new treatment strategies and clinical trial designs for this population, Gao said