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Others worry that once access is granted, it may be difficult to reverse course if costs continue climbing

He shopped his idea around at the Department of Veterans Affairs, where he worked at the time, as well as several different pharmaceutical companies, but didn't have much success

These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)

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Only a head-to-head randomized controlled trial could definitively establish superiority, and that trial has not been conducted

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