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Tirzepatide (Mounjaro, ZepBound): This dual-action medication mimics both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP, another naturally occurring hormone), resulting in even greater weight loss for many people

Then, 480 SYBR green dye was used for quantitative real-time PCR

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it works upstream, on an enzyme called nicotinamide N-methyltransferase (NNMT) that fat cells over-express when they become metabolically sluggish