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Even though the PLC/PKC signaling pathway has been shown to be involved in GLP-1-induced insulin secretion in mouse pancreatic cells [56], this signaling pathway was unlikely involved in the effect of exendin-4 on GABA currents in GCs, due to the persistence of this effect when PI-PLC or PC-PLC was blocked (Fig

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[DOI] [PubMed] [Google Scholar] 23.Sartorius K., Emtestam L., Jemec G.B., Lapins J