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These two conditions are closely interrelated, with DM representing a significant risk factor for CVD due to factors such as obesity, hypercholesterolemia, atherosclerosis, microcirculation disorders, and hypertension [1, 2]

Maintaining consistent hydration from the outset of therapy prevents volume depletion

Patients should never alter prescribed doses without medical guidance

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In a separate study, administering 500 mg of BBR twice daily resulted in significant reductions in total cholesterol (29 %), triglycerides (35 %), and LDL-C (25 %) among 32 hyperlipidemic Asian patients compared to a placebo group [52]

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