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Description
Individual responses will vary

The switch from tirzepatide to semaglutide is the most common transition and is generally well tolerated

More serious but less common risks include pancreatitis, gallbladder disease, and acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms)
63 Based on these favorable findings, cagrilintide has advanced to phase 3 clinical trials and is currently under active investigation as a potential first-in-class amylin-based pharmacotherapy for obesity

Weight-loss benefit builds as the dose climbs toward the 2.4 mg maintenance target

Of those people, some experienced side effects not observed in clinical trials, specifically body temperature and hormonal/menstrual disruptions
