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doi:10.7326/annals-25-00860.

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Pfizer halted development of its oral GLP-1 danuglipron in 2025 after a trial participant developed liver injury, reflecting safety concerns that require ongoing monitoring with real-world data

GLP-1 injections, also known as glucagon-like peptide-1 receptor agonists, are a treatment originally developed for managing type 2 diabetes
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It should be noted that the the Food and Drug Administration has addressed concerns about unapproved GLP-1 drugs used for weight loss