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But human observational evidence is increasingly reassuring on major malformations when confounding is handled carefullyfor example, large datasets show no substantial increased risk of major congenital malformations with early exposure, and a European teratology cohort reported no increase in major birth defects vs diabetes/high-BMI comparators

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Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: This study analyzed de-identified EHR data from a network of tertiary clinical centers tied to academic medical centers in the United States through the nference nSights Analytics Platform [10-11]

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With the data we have so far, GLP-1 receptor agonists really are blockbuster drugs