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Utility of neuronal-derived exosomes to examine molecular mechanisms that affect motor function in patients with parkinson disease: a secondary analysis of the exenatide-PD trial

4ac), revealing the essential role of CNS GIPR for the maximal weight loss response to combined GIPR blockade/GLP-1R activation

Briskey, D., Malfa, G

Diabetes 55 , 14841490 (2006)

Furthermore, obesity and T2DM lead to systemic inflammation, increasing pro-inflammatory brain cytokines, which may, in turn, interfere with insulin signaling and neurotransmission [92]

Vomiting, diarrhea and constipation occur less frequently but still affect notable numbers of patients