what was the first glp 1 drug List of GLP-1 Receptor Agonists for Diabetes & Weight Loss GLP-1 Agonists: A Comprehensive Overview
Description
Once-weekly glucagon-like peptide-1 receptor agonist dulaglutide significantly decreases glycated haemoglobin compared with once-daily liraglutide in Japanese patients with type 2 diabetes: 52 weeks of treatment in a randomized phase III study

This difference comes with both pros and cons

Collagen Breakdown: Losing fat faster than skin can retract leads to ozempic loose skin
Patients with RA should continue evidence-based DMARD therapy as recommended by the American College of Rheumatology, while any GLP-1 use should be reserved for approved indications such as diabetes or weight management under appropriate medical supervision

First description in humans of the ability of SGLT2 inhibitors to attenuate glomerular hyperfiltration, likely by affecting tubuloglomerular feedback mechanisms

Adding another layer of complexity, a multinational survey revealed that only 26% of clinicians viewed obesity as a chronic disease, and fewer than half routinely recorded it as such in patients medical files (Dixon et al., 2025)
