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A recent nationwide estimate of obesity indicated that 42% of adults aged 20 and over are obese

These older drugs also have anticholinergic effects, meaning that they block the slowing effect of our own acetylcholine on heart rate, and can have adverse reactions on the heart when used with monoamine oxidase inhibitor drugs often still used to treat depression

Mechanisms may involve effects on satiety signaling, food reward pathways, and brain areas mediating feeding behaviors

Common side effects like nausea typically diminish after the first few weeks as your body adjusts to the medication

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