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Given the promising research in organ fibrosis and the reduction in chronic low-grade inflammation and joint fibrosis in arthritis [1], I think this is likely, but research is needed

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Common side effects reported with retatrutide include: Nausea, vomiting, and diarrhoea (most frequent, particularly during dose escalation) Decreased appetite Constipation Injection site reactions Mild increases in heart rate Cagrilintide has demonstrated a generally well-tolerated profile, with gastrointestinal symptoms also being the most commonly reported adverse effects

- Cleveland Clinic
