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Reduce if gastrointestinal symptoms remain severe after six or more weeks at a given dose level, if significant dehydration results from persistent vomiting or diarrhea, if heart rate increases beyond 15 beats per minute above baseline, or if the side effect burden is causing protocol abandonment

The maximum recommended dosage is 2.4 mg (48 units) per week

Because of these properties, GLP-1 pathways have become a significant focus in metabolic and endocrine research

The PlexusDx Precision Peptide Genetic Test ($99 add-on) examines 14 pathways and 150+ genetic insights related to peptide metabolism, including variants in GLP1R and GIPR genes

Before starting, continuing, or stopping any weight loss medication, it is strongly advisable to speak with your GP or a healthcare professional who can assess your individual circumstances

For example, both medications contain semaglutide as an active ingredient, which helps in managing body weight