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It's a hormone a peptide your body produces in response to eating

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doi: 10.1007/s00125-022-05715-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 196.Yu Y, Hu G, Yin S, et al

A 2025 preclinical study in Cancer & Metabolism examined Retatrutide, also identified as LY3437943, in obesity-associated pancreatic cancer model systems

In vitro , the DPP4 release increased substantially during fat cell differentiation, and comparison with preadipocytes and adipose tissue, macrophages showed that adipocytes most likely represent the major source of DPP4 released from the intact organ to the circulation