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doi: 10.3748/wjg.v21.i40.11353 57 MarsR

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Metformin HCl Renal clearance is approximately 3.5times greater than creatinine clearance, which indicates that tubular secretion is the major route of metformin elimination

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In a combined multiple ascending dose (MAD) and Phase 2a study in people with type 2 diabetes over 41 days, the safety of cotadutide was confirmed (83)

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