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The novel incretin agonist, named I-M-150847, promotes robust glucose-stimulated insulin exocytosis in cultured pancreatic beta cells

Between 2025 and 2030, the global pharmaceutical industry faces a Loss of Exclusivity (LOE) wave that puts an estimated $200 billion to $400 billion in branded drug revenue at direct risk.

Updating our priors after the one-year anniversary of our original GLP-1 Primer

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Results At week 4 after discontinuation, compared with the control group, AOM treatment still had weight loss effect (WMD=0.32 kg, 95% CI3.602.97, P=0.85, I2=83%)

The search for over-the-counter GLP-1 alternatives reflects growing interest in weight loss support