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GLP-1 and its analogs exhibit bloodbrain barrier penetrance, enabling direct modulation of central nervous system function 68

Your dose will likely increase, provided you havent had any bothersome side effects and need to lose more weight

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Long-term incidence of gallstone disease after bariatric surgery: results from the nonrandomized controlled Swedish Obese Subjects study

ClinicalTrials.gov registration: NCT06659744, NCT07088718, NCT07096063

The SURMOUNT-1 trial, published in the New England Journal of Medicine, randomized 2,539 adults with obesity or overweight to tirzepatide 5 mg, 10 mg, or 15 mg weekly for 72 weeks