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Description
Exenatide is a non-human peptide analogue originally isolated from the saliva of the Gila monster ( Heloderma suspectum )

S7A, GLP-1RA intervention was associated with a reduction in total cholesterol when compared to placebo (MD = 0.04

Table 2: Glucagon-like peptide 1 receptor agonists (GLP-1 RAs): a comparison of common adverse effects in head-to-head trials

HFpEF is characterized by the presence of different comorbidities such as type-2 diabetes mellitus (T2DM), visceral obesity and ageing, all contributing to systemic metabolic inflammation [7, 8]
Zepbound contains the same active ingredient, tirzepatide, as Mounjaro, which is also made by Lilly and is FDA-approved to treat Type 2 diabetes

In vitro studies suggest that GLP-1 has effects on numerous renal cell populations, including glomerular endothelial cells